Gossip Girl is an American teen drama series based on the book series of the same name written by Cecily von Ziegesar. The series was created by Josh Schwartz and Stephanie Savage, and premiered on The CW on September 19, 2007. Narrated by the omniscient yet unseen blogger "Gossip Girl", voiced by Kristen Bell, the series revolves around the lives of privileged young adults on Manhattan's Upper East Side in New York City.

The series begins with the return of Serena van der Woodsen (Blake Lively) from a mysterious stay at a boarding school in Connecticut. Blair Waldorf (Leighton Meester), who creators describe as the queen at the center of their chess game, is a longtime friend and occasional rival of Serena's, and the Queen Bee of Constance Billard School's social scene. The story also follows Chuck Bass (Ed Westwick), the bad boy of the Upper East Side, Nate Archibald (Chace Crawford), Chuck's best friend, and other characters of the turbulent Manhattan scene: Dan Humphrey (Penn Badgley), Nate's friend and Serena's on-again, off-again ex; Vanessa Abrams (Jessica Szohr), Dan's best friend; and Dan's ambitious sister Jenny Humphrey (Taylor Momsen).

Showrunners have revealed they have a "definite endgame in mind" and know how the series will end but not in the near future.